| A Case of Maternal Phenylketonuria Syndrome Presenting With Unilateral Renal Agenesis - Journal of Tropical Pediatrics |
| Gokmen T et al. – The authors hereby present a case who underwent investigations due to the presence of microcephaly and congenital cardiopathy. The diagnosis of PKU syndrome of the mother was determined following assessment of the baby. Furthermore, the unilateral renal agenesis that was detected in this case is the first case reported in the literature in which mPKU accompanies renal agenesis.... |
| Diagnostic Modalities for Gastro-Esophageal Reflux in Infantile Wheezers - Journal of Tropical Pediatrics |
| Patra S et al. – The agreement between positivity of these two tests is best among children between 7 and 12 months of age. Overall GI scintiscan was a better test with higher sensitivity and specificity as compared to 24–h pH study when compared with the history suggestive of reflux and clinical response with anti–reflux treatment as standard. Conclusion: Both GER scan and 24–h pH study are complimentary to each other, however, if both the tests are available then GI scintiscan is better as a single test for GER in these early wheezers.... |
| Do Immunosupressive Patients Really have a Severe Outcome with H1N1 Virus Infection? - Journal of Tropical Pediatrics |
| Akyuz S et al. – The virus affects people at all ages, and school–aged children have the highest rates of infection. Chronic lung disease, immunosuppression and pregnancy are risk factors for seasonal influenza and pandemic influenza as well. Here, authors report five immunosuppressive patients due to various diseases infected with H1N1 influenza and who were completely revealed after promptly treatment with oseltamivir.... |
| Sexually transmitted diseases in children in India - Indian Journal of Dermatology, Venereology and Leprology |
| Dhawan J et al. – STDs in children can be acquired via sexual route or, uncommonly, via non–sexual route such as accidental inoculation by a diseased individual. Neonatal infections are almost always acquired intrauterine or during delivery. Voluntary indulgence in sexual activity is also an important factor in acquisition of STDs in childhood. Sexual abuse and sex trafficking remain the important problems in India. Surveys indicate that nearly half of the children are sexually abused. Most at risk children are street–based, homeless or those living in or near brothels. Last two decades have shown an increase in the prevalence of STDs in children, though most of the data is from northern part of the country and from major hospitals. However, due to better availability of antenatal care to majority of women, cases of congenital syphilis have declined consistently over the past two–three decades. Other bacterial STDs are also on decline. On the other hand, viral STDs such as genital herpes and anogenital warts are increasing. This reflects trends of STDs in the adult population. Concomitant HIV infection is uncommon in children. Comprehensive sex education, stringent laws to prevent sex trafficking and child sexual abuse, and antenatal screening of all the women can reduce the prevalence of STDs in children.... |
| Cutaneous tuberculosis in children: The Indian perspective - Indian Journal of Dermatology, Venereology and Leprology |
| Singal A et al. – Cutaneous tuberculosis continues to be a significant medical problem even with the advent of highly effective antituberculous drugs. It constitutes about 1.5% of all extra pulmonary tuberculosis. The prevalence in children varies from 18 to 54% in India. There is no gender predilection and the infection occurs with increased frequency in 10–14 year age group. Intrafamilial source of TB has been observed very frequently. A concomitant TB lymphadenitis is most common while involvement of other systemic organs like lung, bone and abdomen has also been observed. Protective efficacy of BCG is debatable and not yet fully defined. Of all the clinical types, scrofuloderma (SFD) is the most commonly encountered variant followed by lupus vulgaris (LV) and tuberculosis verrucosa cutis (TBVC). Lichen scrofulosorum (LS) is generally found to be associated with systemic TB focus in about 72% of cases. The impact of HIV on childhood cutaneous TB seems to be minimal.... |
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