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September 03, 2010 CNE ArticleFeasibility of Family Participation in a Delirium Prevention Program for Hospitalized Older Adults - Journal of Gerontological Nursing Rosenbloom–Brunton DA et al. – These findings have implications for clinicians committed to delivering quality inpatient care to older adults and their families, with the benefits of HELP being extended to include family caregivers with an important role in delirium prevention efforts.... Probabilistic learning and inference in schizophrenia - Schizophrenia Research Averbeck BB et al. – The authors found that patients did show a jumping to conclusions style; and those who picked early in the beads task tended to learn less from positive feedback in the sequence task. This favours the likelihood of patients selecting early because they have a low threshold for making decisions, and that they make choices on the basis of relatively little evidence.... Mental Health Attitudes Among Rural and Urban Older Adults - Clinical Gerontologist Hayslip B et al. – These findings suggest that public policy makers and mental health providers should consider the interactive roles of culture–environment, personality, and attitudes toward mental health services when designing mental health programs for older adults.... Management of Neuropsychiatric Symptoms in People with Dementia - CNS Drugs Ballard C et al. – It is important in most situations to limit the use of antipsychotic medication to short–term treatment (up to 12 weeks) of severe neuropsychiatric symptoms to limit harm. Non–pharmacological therapies offer a viable and effective alternative in many situations. Adequately powered randomized controlled trials for the treatment of clinically significant agitation are urgently needed to explore alternative pharmacological therapies.... The Association between Conventional Antidepressants and the Metabolic Syndrome: A Review of the Evidence and Clinical Implications - CNS Drugs McIntyre RS et al. – Conventional antidepressants exert variable effects on constituent elements of the metabolic syndrome, inviting the need for careful consideration prior to treatment selection and sequencing. Initiating and maintaining antidepressant therapy should include routine surveillance for clinical and/or biochemical evidence suggestive of the metabolic syndrome.... Effects of Guanfacine Extended Release on Oppositional Symptoms in Children Aged 6-12 Years with Attention-Deficit Hyperactivity Disorder and Oppositional Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial - CNS Drugs Connor DF et al. – In this population of children aged 6–12 years with ADHD and the presence of oppositional symptoms, significant reductions in CPRS–R:L oppositional subscale and ADHD–RS–IV total scores were observed with guanfacine XR treatment compared with placebo. Treatment with guanfacine XR at optimized doses was associated with mostly mild or moderate TEAEs. The findings of this study support the efficacy of guanfacine XR in the treatment of children with ADHD and the presence of oppositional symptoms.... Escitalopram: A Review of its Use in the Management of Major Depressive Disorder in Adults - CNS Drugs Garnock–Jones KP et al. – Escitalopram is an effective and generally well tolerated treatment for moderate to severe MDD. Escitalopram, like other SSRIs, is an effective first–line option in the management of patients with MDD.... Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness - Cancer Epidemiology, Biomarkers & Prevention Williams JM et al. – Anti–epileptic drugs (AED) are increasingly used in the management of serious mental illness yet their effects on nicotine metabolism have not been studied. CBZ likely induces hepatic metabolism via CYP2A6 and is associated with increased 3HC/Cotinine ratios. Increased nicotine metabolism in individuals using AED has implications for increased smoking behavior and exposure to more tobacco toxins that warrants further study.... Development of a universal psycho-educational intervention to prevent common postpartum mental disorders in primiparous women: a multiple method approach - BMC Public Health Rowe HJ et al. – What Were We Thinking! is a postnatal mental health intervention which has the potential to contribute to psychologically–informed routine primary postnatal health care and prevent common mental disorders in women.... Follow-up of adolescents born extremely preterm: Self-perceived mental health, social, and relational outcomes - Acta Pediatrica Hallin AL et al. – Extremely preterm born adolescents did not experience more problems regarding mental health compared to controls. Nevertheless, they reported less social interaction and, to a greater extent, a negative model of self.... More News...