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February 08, 2010 Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction - Evidence-based Complementary and Alternative Medicine Puranik AS et al. – The studies indicate that both these extracts are pharmacologically safe and did not show any significant adverse reactions at the tested doses. The traditional hydro–alcoholic extract did not show any significant effect on pharmacokinetics; however, the technology–based supercritical extract caused a significant reduction in absorption of metformin. These results indicate the need to include pharmacokinetic herb–drug interaction studies as evidence for safety especially for technology–based extracts.... Grape seed beneficial in fight against cancer and heart disease - The Clinical Advisor Sego S et al. – We are well aware of the constant damage done to our cell structures by oxidative effects from free radicals and other proinflammatory entities. While grape seed is certainly not the only natural compound to exert these protective effects, it is worth considering when consulting with patients about their health. Careful attention should be paid, however, to the significant drug interaction profile of grape seed, and patients should be screened for the use of these medications.... The Addition of Cervical Thrust Manipulations to a Manual Physical Therapy Approach in Patients Being Treated for Mechanical Neck Pain: A Secondary Analysis - Journal of Orthopaedic & Sports Physical Therapy Boyles RE et al. – Clinically meaningful and statistically significant improvements in both subgroups of patients over time suggest that cervical thrust manipulation as part of the MPT treatment plan did not influence the results of the treatment arm of the larger RCT from which this study was drawn. Although no between–group differences can be identified, the small observed effect sizes in this study may benefit future studies with sample size estimation for larger RCTs and indicate the need to incorporate clinical prediction rule criteria as a means to improve statistical power.... Feasibility, inter- and intra-rater reliability of physiotherapists measuring prolapse using the pelvic organ prolapse quantification system - International Urogynecology Journal Stark D et al. – POP–Q is a feasible and reliable outcome measure for physiotherapists to use.... The long-term effects of naprapathic manual therapy on back and neck pain - Results from a pragmatic randomized controlled trial - BMC Musculoskeletal Disorders Skillgate E et al. – Combined manual therapy, like naprapathy, is effective in the short and in the long term, and might be considered for patients with non–specific back and/or neck pain.... Physiological and Emotional Responses of Disabled Children to Therapeutic Clowns: A Pilot Study - Evidence-based Complementary and Alternative Medicine Kingsnorth S et al. – The results suggest that this popular psychosocial intervention has a direct and positive impact on hospitalized children. This pilot study contributes to the current understanding of the importance of alternative approaches in promoting well–being within healthcare settings.... Acupuncture Treatment of a Patient with Persistent Allergic Rhinitis Complicated by Rhinosinusitis and Asthma - Evidence-based Complementary and Alternative Medicine Kim AR et al. – A 48–year–old male suffering from persistent allergic rhinitis with comorbid chronic rhinosinusitis and asthma since the age of 18 years was studied. He complained of nasal obstruction, sneezing, cough, rhinorrhea and moderate dyspnea. The patient was treated with acupuncture, infrared radiation to the face and electro–acupuncture. Needles were inserted at bilateral LI20, GV23, LI4 and EX–1 sites with De–qi. Electro–acupuncture was performed simultaneously at both LI20 sites and additional traditional Korean acupuncture treatments were performed.... February 05, 2010 Complementary, Holistic, and Integrative Medicine: Headaches - Pediatrics in Review Kemper KJ et al. – Complementary and alternative medical (CAM) therapies are used commonly to prevent and treat headaches. Children and adolescents often have headaches; among adolescents, more than 50% of boys and more than 70% of girls report having had a headache in the previous month. Headache management typically includes acute treatment, preventive measures, and biobehavioral therapies. ... In Vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease - Phytotherapy Research Abdel–Sattar E et al. – Argemone ochroleuca showed pronounced activity against P. falciparumGHA and T. cruzi with low cytotoxicity against MRC–5 cells. Capparis spinosa (EtOAc fraction) showed pronounced activity against P. falciparumGHA with an IC50 0.50 mug/mL in the absence of toxicity against MRC–5 cell line. Heliotropium curassavicum (CHCl3 fraction) showed similar activity against P. falciparum. These three extracts will be subjected for further extensive studies to isolate and identify their active constituents.... Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells - Evidence-based Complementary and Alternative Medicine Johnston MF et al. – The key contribution of this article involves the use of cellular immunology and molecular biological theory to interpret and synthesize evidence from disparate animal and human studies in formulating the ‘acupuncture immuno–enhancement hypothesis’: clinicians may use acupuncture to promote the induction and secretion of NK–cell activating cytokines that engage specific NK cell receptors that endogenously enhance anticancer immune function.... More News...