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September 03, 2010
Substantial Morbidity for Hospitalized Children With Community-Acquired Rotavirus Infections: 2005-2007 IMPACT Surveillance in Canadian Hospitals - The Pediatric Infectious Disease Journal
Le Saux N et al. – The authors describe community–acquired rotavirus illness in 1359 children hospitalized at 12 centers in Canada between January 2005 and December 2007. The median age was 1.5 years. Almost half (48.6%) had significant dehydration, almost one–fifth (19%) had clinical sepsis and 7% had seizures at presentation. The median hospital stay was 3.4 days. Severe clinical presentations are less commonly described in surveillance programs....
Recruitment of a Community-based Cohort for Research on Diversity and Risk of Dementia - Alzheimer Disease & Associated Disorders
Hinton L et al. – The community screen identified candidates for an in depth clinical evaluation and enrollment in longitudinal research, and the authors examined factors that predicted a positive response to invitation for the clinical evaluation. Individuals with a broader fund of knowledge were more likely to participate independent of other variables including ethnicity and education. When diversity is an important goal active outreach is far more efficacious than clinic–based and advertising–based approaches to recruitment....
Community-based prevention leads to an increase in condom use and a reduction in sexually transmitted infections (STIs) among men who have sex with men (MSM) and female sex workers (FSW) - BMC Public Health
Gutierrez JP et al. – Important changes in behaviours related to an increase in prevention activities translated to reductions in STI sero–prevalence in AP, India. In contrast with non–FPP sites, the FPP sites experienced an intense community approach as part of the FPP intervention, and the general increase in condom use and its effect on STI sero–prevalence reflected the efficacy of these intense prevention activities focused on key populations in AP....
Violence against women: The perspective of academic women - BMC Public Health
Kalaca S et al. – Academic women introduced an ecological approach for the explanation of VAW by stressing the importance of taking into account the global context of the occurrence of VAW. Similar studies with various community members –including men– will help to define targeted interventions....
Child mortality from solid-fuel use in India: a nationally-representative case-control study - BMC Public Health
Bassani DG et al. – Child mortality risks, from all causes, due to solid fuel exposure were lower than previously, but as exposure was common solid, fuel caused 6% of all deaths at ages 0–4, 20% of deaths at ages 1–4 or 128 000 child deaths in India in 2004. Solid fuel use has declined only modestly in the last decade. Aside from reducing exposure, complementary strategies such as immunization and treatment could also reduce child mortality from acute respiratory infections....
Case-Mix Adjustment and Enabled Reporting of the Health Care Experiences of Adults With Disabilities - Archives of Physical Medicine and Rehabilitation
Palsbo SE et al. – Self–reported activity limitations incorporating standard questions from the American Community Survey can be used to create a disability case–mix index and to construct profiles of a population's activity limitations. The enabled comparative report, which we call the Assessment of Health Plans and Providers by People with Activity Limitations, is more cognitively accessible than typical CAHPS report templates for state Medicaid plans. The CAHPS Medicaid reporting tools may provide misleading ratings of health plan and physician quality by people with disabilities because the mean ratings do not account for systematic biases associated with disability. More testing on larger populations would help to quantify the strength of various reporting biases....

September 02, 2010
Generalizability of clinical trials for cannabis dependence to community samples - Drug and Alcohol Dependence
Okuda M et al. – The results also support the notion that clinical trials tend to recruit highly selective samples, rather than adults who are representative of typical patients. Clinical trials should carefully evaluate the effects of eligibility criteria on the generalizability of their results. Even in efficacy trials, stringent exclusionary criteria could limit the representativeness of study results....
Exploring Disparities and Variability in Perceptions and Self-Reported Colorectal Cancer Screening Among Three Ethnic Subgroups of U. S. Blacks - Oncology Nursing Forum
Gwede CK et al. – This exploratory, developmental pilot study identified lack of awareness, low risk perception, and distinct barriers to screening. The findings support the need for a larger community–based study to elucidate and address disparities among subgroups....
Community Management of Anti-malarials in Africa and Iatrogenic Risk - Journal of Tropical Pediatrics
Orostegui L et al. – A persistent fever suspected to be due to malaria was treated inappropriately with atovaquone–proguanil and then with sulfadoxine–pyrimethamine again. Cumulative toxicity of anti–malarials leads to irreversible hepatic damages requiring hepatic transplantation. Community caretakers must be aware of the potential side effects and the contraindications of anti–malarials. Early identification of drug–induced toxicity and immediate discontinuation of the drug are the more effective tools to limit the progression of tissue damage....
Estimation of Prostate Size in Community-dwelling Men - Urology
Jacobson DJ et al. – The study uses two population–based samples of prostate cancer–free men to develop and validate a novel multivariable equation for estimating prostate volume (PV). Previous investigators have demonstrated the ability to use serum prostate–specific antigen (PSA) levels to estimate PV in men without prostate cancer; however, the ability of additional clinical variables to further enhance PV estimation in these men remains unclear. The data suggest that PV can be estimated with easily obtained clinical variables. Moreover, the authors demonstrate that age and weight can be added to PSA level to achieve greater accuracy in predicting PV. This methodology may prove useful for estimating PV in men in settings where costs and practicality preclude the use of imaging techniques....

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