| Agreeableness and Activity Engagement in Nursing Home Residents with Dementia - Journal of Gerontological Nursing |
| Hil NL et al. – This pilot study used an analysis of covariance procedure to test the relationship between the personality trait of agreeableness and engagement when activities are ideally tailored to ability and interest. No significant difference was found between the high and low agreeableness groups, indicating that residents were more engaged when activities were individually tailored, regardless of their agreeableness level. Although low agreeableness may pose a challenge when implementing activities for people with dementia, the results of this study suggest that tailoring activities to functional ability and interest may overcome the effects.... |
| Metronomic Chemotherapy for Metastatic Prostate Cancer: A 'Young' Concept for Old Patients - Drugs & Aging |
| Fontana A et al. – Metronomic chemotherapy, i.e. low–dose, long–term, frequently administered chemotherapy, has been shown to have a significant stabilizing effect on cancer and a positive impact on the quality of life of patients, including those with prostate cancer. Given the low toxicity profile of metronomic chemotherapy, elderly patients or patients with co–morbidities may be candidates for a first–line or second–line oral metronomic approach when standard chemotherapies are contraindicated or not acceptable to the patient. Moreover, the possibility of patients being able to spend more time at home is an important component of a palliative treatment such as metronomic chemotherapy. Unfortunately, and despite these considerations, very few data are available on the activity and safety of metronomic chemotherapy in elderly patients.... |
| Age-related physiologic changes and perioperative management of elderly patients - Surgical Oncology |
| Colloca G et al. – Aging is associated with a progressive decrease in heart, lung and kidney performance. Under normal conditions, these physiologic changes do not produce any problems for the elderly, but when these patients are subjected to the stress of surgery or its complications, there may be inadequate functional reserve. It is very important to know age–related patho–physiological changes in order to be able to better evaluate elderly patients undergoing surgery, and to prevent and manage preoperative complications.... |
| Schizophrenia in older adults - Current Psychiatry |
| Desai AK et al. – Positive symptoms of schizophrenia—hallucinations, delusions, and disorganized or catatonic behavior—do not "burn out" in most older adults. The severity of "day–to–day" psychotic symptoms appears reduced in patients with schizophrenia who have not had recent severe psychotic episodes. Aging–associated decrease in dopaminergic and other monoaminergic activities may explain this.... |
| Assessment and treatment of elderly patients with cancer - Surgical Oncology |
| Balducci L et al. – Aging, age–related changes, frailty, prolongation of active life expectancy, prevention of Adverse Drugs Reactions (ADRs), Comprehensive Geriatric Assessment (CGA), and individualised treatment in the future will become the most widely used concepts in the management of cancer patients.... |
| Associations between energy demands, physical activity, and body composition in adult humans between 18 and 96 y of age - American Journal of Clinical Nutrition |
| Speakman JR et al. – Physical activity level and activity energy expenditure were not associated with age in subjects aged <52 y. activity energy expenditure, basal energy expenditure, and PAL were all negatively associated with age in subjects aged >=52 y. An absence of a relation between age–adjusted physical activity level and fat–free mass suggested that greater physical activity was not associated with higher fat–free mass in the elderly.... |
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