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May 09, 2008
Complete Atrioventricular Block Associated With Concomitant Use of Metoprolol and Paroxetine - Mayo Clinic Proceedings
Onalan O et al. - We report the first case of complete atrioventricular block associated with coadministration of paroxetine and metoprolol. Increasing physicians’ awareness of drug-induced severe bradyarrhythmia might prevent unnecessary implantation of permanent pacemakers....
Monitoring Cholesterol Levels: Measurement Error or True Change - Annals of Internal Medicine
Glasziou P et al. - This analysis of data from a trial that compared pravastatin with placebo in patients with coronary disease found that the signal–noise ratio in cholesterol monitoring was weak. Consider testing adherent patients with well-controlled cholesterol levels every 3 to 5 years rather than every few months or annually. ...
Early detection and efficient therapy of cardiac angiosarcoma due to routine transesophageal echocardiography after cerebrovascular stroke - Vascular Health and Risk Management
Vogelgesang D et al. - A 59-year-old female presented with symptoms of cerebral ischemia. A computed tomography (CT) scan showed changes suggestive of stroke. Transesophageal echocardiography revealed an inhomogeneous, medium-echogenic, floating mass at the roof of the left atrium near the mouth of the right upper pulmonary vein, indicative of a thrombus. Although cardiac angiosarcoma is a rare disease, it should be taken into consideration as a potential cause of cerebral embolic disease....
Oral Disopyramide for the Acute Treatment of Severe Outflow Obstruction in Hypertrophic Cardiomyopathy in the ICU Setting - Chest
Sirak TE et al. - Transthoracic echocardiography revealed massive asymmetric septal hypertrophy and a diffusely hyperkinetic left ventricle with a left ventricular outflow tract (LVOT) gradient of 92 mm Hg. Two and a half hours after oral administration of disopyramide, LVOT gradient had decreased to 25 mm Hg with a corresponding immediate improvement in symptoms....
Identification of Target Antigens of Antifibroblast Antibodies in Pulmonary Arterial Hypertension - American Journal of Respiratory and Critical Care Medicine
Terrier B et al. - AFAs detected in patients with PAH recognize cellular targets playing key roles in cell biology and maintenance of homeostasis....
Sudden Cardiac Arrest and Early Repolarization - New England Journal of Medicine
Haissaguerre M et al. - Among patients with a history of idiopathic ventricular fibrillation, there is an increased prevalence of early repolarization....
Risk Stratification for Recurrent Heart Failure in Patients Post-Myocardial Infarction With Electrocardiographic and Echocardiographic Left Atrial Abnormality - The American Journal of Cardiology
Ariyarajah V et al. - Our data suggest that a combination of electrical and mechanical left atrial dysfunction is significantly more predictive of increased cardiovascular events and mortality compared with left atrial mechanical dysfunction alone....
Pregnancy Associated Plasma Protein A, a Novel, Quick, and Sensitive Marker in ST-Elevation Myocardial Infarction - The American Journal of Cardiology
Iversen KK et al. - PAPP-A levels are elevated in >90% of patients presenting with STEMIs if measured <6 hours after the onset of symptoms or <2 hours of primary percutaneous coronary intervention. In the early stages of STEMI, PAPP-A seems to be a more sensitive marker of myocardial infarction than CKMB and troponin T....
Prognostic Value of Normal Adenosine-Stress Cardiac Magnetic Resonance Imaging - The American Journal of Cardiology
Pilz G et al. - Our results provide clinical reassurance that patients at risk for CAD-associated MACE were not missed by CMR. Hence, CMR may serve as a reliable noninvasive gatekeeper to reduce the number of redundant coronary angiographies....
The impact of comorbidity burden on the cardiovascular risk in the Peripheral Arteriopathy and Cardiovascular Events study - QJM: An International Journal of Medicine
Brevetti G et al. - Our findings indicate that overall comorbidity, and not only cardiovascular comorbidity, must be considered for prediction of myocardial infarction and stroke in PAD....
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