| Cardiac Safety of Methylphenidate Versus Amphetamine Salts in the Treatment of ADHD - Pediatrics |
| Winterstein AG et al. - Exposure to methylphenidate and amphetamines salts showed similar risk for cardiac ED visits. Additional population-based studies that address manifestation of serious heart disease, especially after long-term use, dosage comparisons, and interactions with preexisting cardiac risk factors are needed to inform psychiatric treatment decisions.... |
| In-hospital versus out-of-hospital pediatric cardiac arrest: A multicenter cohort study - Critical Care Medicine |
| Moler F et al. - For pediatric CA with ROC, several major differences exist between IH and OH cohorts. The finding that the etiology of death was attributed to neurologic indications much more frequently in OH arrests has important implications for future research. Investigators planning to evaluate the efficacy of new interventions, such as TH, should be aware that the IH and OH populations differ greatly and require independent clinical trials.... |
 The Recent Concept of Heart Function in Elderly Patients - Clinical Medicine: Geriatrics |
| Wake R et al. - An epidemic increase in heart failure (HF) mortality, hospitalization, and prevalence rates has been observed among older persons associated with increased an incidence and improved survival in recent years, in spite of a decrease in coronary artery and cerebrovascular disease mortality. Importantly, increases in HF mortality and morbidity rates were confined to the population over 65 years of age in the Framingham study. In contrast to middle-aged patients with HF, factors other than left ventricular (LV) systolic dysfunction contribute to HF in older patients. Epidemiological studies have established that 40 to 80 percent of older patients with heart failure, despite preserved ejection fraction without valve disease, are attributed to LV diastolic dysfunction.... |
| Psychosocial Modulators of Angina Response to Myocardial Ischemia - Circulation |
| Arnold SV et al. - Among patients with a similar burden of inducible ischemia, a history of coronary revascularization and current anxiety and depressive symptoms were associated with more frequent angina. These results support the study of angina treatment strategies that aim to reduce psychosocial distress in conjunction with efforts to lessen myocardial ischemia.... |
July 01, 2009
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| A systematic review of the cardiovascular risk of inhaled anticholinergics in patients with COPD - International Journal of COPD |
| Hilleman DE et al. - The long-term use of inhaled anticholinergic agents has recently been suggested to be associated with an excess risk of adverse cardiovascular (CV) outcomes in patients with COPD. The relative risks for serious CV events, heart failure, and myocardial infarction were all significantly lower with tiotropium than placebo.... |
| Project HeartBeat!: Concept, Development, and Design - American Journal of Preventive Medicine |
| Labarthe DR et al. - Major cardiovascular disease (CVD) risk factors begin development in childhood and adolescence. Project HeartBeat! studied early development of these risk factors as growth processes. Growth, body composition, sexual maturation, major CVD risk factors, and cardiac structure and function were monitored every 4 months for up to 4 years among 678 children and adolescents aged 8, 11, or 14 years at study entry...The mixed-longitudinal design provides trajectories of change with age, for total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides; systolic, and fourth-phase and fifth-phase diastolic blood pressure, and left ventricular mass. These trajectories are then related to concurrent measures of multiple indices of body composition and sexual maturation and adjusted for energy intake and physical activity. The data provide valuable insights into risk factor development and suggest a fresh approach to understanding influences on blood lipids, blood pressure, and left ventricular mass during the period of childhood and adolescence, a period of dynamic change in these risk factors.... |
| Association of Transseptal Punctures with Isolated Migraine Aura in Patients Undergoing Catheter Ablation of Cardiac Arrhythmias - Journal of Cardiovascular Electrophysiology |
| Henrikson CA et al. - This study reports for the first time the incidence and outcomes of isolated migraine aura in patients undergoing electrophysiology procedures involving TSC. For post-TSC patients who present with atypical neurologic symptoms, especially "scintillating scotoma," once transient ischemic attack or other neurologic event has been ruled out, an aura associated with the TSC should be entertained as a possible diagnosis. Electrophysiologists who perform TSC, need to be aware of this phenomenon and can reassure the patients of the transient and benign nature.... |
| Elevated Blood Pressure, Obesity, and Hyperlipidemia - The Journal of Pediatrics |
| Liao CC et al. - This study found a high prevalence of elevated blood pressure in children with abnormal urinalysis results, with a strong association with BMI and total choleterol level.... |
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