| The impact of vitamin D deficiency on diabetes and cardiovascular risk - Current Opinion in Endocrinology, Diabetes and Obesity |
| Baz–Hecht M et al. – The high prevalence of vitamin D deficiency and plausible molecular mechanisms linking this to diabetes and cardiovascular risk suggest treatment of vitamin D deficiency to prevent and/or treat diabetes is a promising field to explore.... |
| Mixing NSAIDs with antiplatelet therapy - The Clinical Advisor |
| Sherman C – With the aging of the population, use of nonsteroidal anti–inflammatory drugs for musculoskeletal discomfort and other indications has risen. The guideline's overarching message is that patients who are at risk of adverse GI effects should have gastroprotection. Gastroprotection is virtually mandatory for patients receiving combined aspirin and anticoagulant therapy. Once bleeding develops and cardioprotection is suspended, the situation can rapidly spiral out of control. ... |
| The management of pain in end-stage heart failure - British Journal of Cardiac Nursing |
| Hughes S et al. – Pain is emerging clinically as an important but overlooked symptom in heart failure. The symptom of pain is poorly described in chronic disease and not a symptom immediately associated with heart failure. Despite this, in studies pain is commonly reported by heart failure patients. Heart failure patients may experience pain from a variety of causes, which may be acute, chronic or in end–stage disease, the concept of 'Total Pain' may apply. Treatment can be a challenge as it must take into account any contraindications the patient's diagnosis or other medications impose. Established pain management may need to be adapted to include a combination of drugs with different modes of action and non pharmacological strategies.... |
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